This fall, I will be teaching a course titled “Biotechnology: Techniques and Data Analysis” and will use the textbook aptly titled “Biotechnology”. As I familiarize myself with the book, I have found it difficult to pin down which chapters to cover. The chapters in the book are as follows:
Chapter 1: Basics of Biotechnology
Chapter 2: DNA, RNA, and Protein
*Chapter 3: Recombinant DNA Technology
*Chapter 4: DNA Synthesis In Vivo and In Vitro
*Chapter 5: RNA-Based Technologies
*Chapter 6: Immune Technology
Chapter 7: Nanobiotechology
*Chapter 8: Genomics and Gene Expression
*Chapter 9: Proteomics
*Chapter 10: Recombinant Proteins
Chapter 11: Protein Engineering
Chapter 12: Environmental Biotechnology
*Chapter 13: Synthetic Biology
Chapter 14: From Cell Phones to Cyborgs
*Chapter 15: Transgenic Plants and Plant Biotechnology
*Chapter 16: Transgenic Animals
Chapter 17: Inherited Defects and Gene Therapy
Chapter 18: Cloning and Stem Cells
Chapter 19: Cancer
Chapter 20: Aging and apoptosis
Chapter 21: Viral and Prion Infections
Chapter 22: Biological Warfare
Chapter 23: Forensic Molecular Biology
*Chapter 24: Bioethics in Biotechnology
(Chapters denoted with an asterisk will be the topics covered in the course.)
One could argue that biotechnology (the modern era at least) started with the development of recombinant DNA technology, so starting with the “Recombinant DNA Technology” chapter is perfect.
Chapters 4, 5, 8, and 9 will essentially walk us through the Central Dogma of Molecular Biology and the techniques that can make use of the cellular processes of this dogma (DNA replication, transcription, and translation).
It might make sense to swap the “Genomics and Gene Expression” topic around with the “Immune Technology” chapter so that we finish up discussing DNA and RNA before moving on to proteins.
Chapter 10’s discussion of “Recombinant Proteins” will see the recombinant DNA technology idea through to its logical conclusion and wrap up the central dogma-centric portion of the course.
The Biotechnology degrees at MSU-Bozeman are split up into three different options: Microbial Systems, Plant Systems, and Animal Systems. To provide a taste of each of these “systems”, we will cover the chapters on “Synthetic Biology”, “Transgenic Plants and Plant Biotechnology”, and “Transgenic Animals”, respectively.
If time allows, the chapter on “Bioethics in Biotechnology” will be the conclusion of this course.
In total, we are scheduled to cover eleven chapters in the 15-week semester. From my experience, this should be about the right amount of material but time will tell if it holds true.
Additional assignments will be designed to allow students to explore the remaining topics thus providing some flexibility for students to tailor the course to their interests.