- Section 2.1 – The Complement System
- Zymogen Cascades in Human Physiological Responses
- Some Components and Cleavage Products of the Complement System
- Complement Activation Pathways: All Roads Lead to C3 Convertase
- Three Functions for C3 Cleavage Products
- How Do Phagocytes Eat Opsonized Cells?
- Formation of Membrane Attack Complexes
- Control Yourself: Autonomous Complement Pathway Regulation
- Pathogens Can Regulate the Complement Pathway, Too!
- Section 2.2 – Pathogen-Associated Molecular Patterns (PAMPs) and Pathogen Recognition Receptors (PRRs)
- PAMPs vs. MAMPs vs. DAMPs
- Molecular Patterns Recognized by Innate Immune Receptors
- Becoming a Danger to One’s Self
- Diversity of PRRs and the Types of PAMPs They Detect
- Cellular Responses Downstream of PAMP Recognition
- Examples of Negative Feedback Mechanisms Following Responses to PAMP Recognition
- If Possible, Pathogens Counteract Innate Immune Responses Related to PAMP Recognition
- Section 2.3 – Inflammation
- Signs and Symptoms of Inflammation: Tumor, Rubor, Calor, Dolor, and Functio Laesa
- A Simplified Framework for Describing the Phases of Inflammation
- Details Related to the Effector Phase of Inflammation
- Ending Inflammation and Restoring Tissue Homeostasis
- Endotoxin Tolerance to LPS and Other TLR-Recognized PAMPs
- Training Innate Immunity Can Enhance Protection
Life and Biology 