I discuss embryonic stem cells and the famous 2006 Cell paper showing that differentiated cells can be reprogrammed to be pluripotent stem cells known as iPS cells (induced pluripotent stem cells). Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors: http://www.ncbi.nlm.nih.gov/pubmed/16... https://youtu.be/3jecVcbEXFk

Here, I present three challenges/laws for the immune system: Universal Tolerant Appropriate Immunity by William E. Paul (http://amzn.to/1IEIvyF) Kuby Immunology by Owen, Punt, and Stranford (http://amzn.to/1NiyuUF) https://youtu.be/sBYJtDqj62A

Here I talk about how CRISPR systems can address some of the biggest problems associated with editing genomes to create transgenic organisms. I also comment on three big applications of CRISPR technology that George Church is excited about. Development and Applications of CRISPR-Cas9 for Genome Editing (Review) http://www.ncbi.nlm.nih.gov/pubmed/24... First successful repair of mutant gene in … Continue reading CRISPR: Big Picture Applications