*YouTube pulled this video without an explanation. My appeal failed.

Stopping virus replication without harming normal cellular processes involves targeting the various steps of virus replication. Many coronaviruses can be inhibited by a molecule that targets the RNA-dependent, RNA polymerase of coronaviruses.

Remdesivir (aka GS-5734) Inhibition of Coronaviruses https://stm.sciencemag.org/content/9/396/eaal3653

Remdesivir inhiits MERS RNA-dependent RNA-polymerase https://www.jbc.org/content/early/2020/02/24/jbc.AC120.013056.abstract

We have come a long way from George Beadle’s “one gene, one enzyme” hypothesis. This video explains how a surprisingly low number of protein-coding genes into a surprisingly large number of protein variations.

Understandably, there has recently been an increased interest in viruses. Here, we will tie our discussion of the Central Dogma of Biology to viruses. The typical flow of genetic information from DNA to RNA to protein is often modified by viruses, which have a variety of genome types.

Building off of the Central Dogma of Molecular Biology episode, we take a close look at RNA and the many functions of these molecules in a cell.

The Central Dogma of Biology provides a foundation for molecular biology. This video goes over the general flow of genetic information, enzymes involved in the process, and an intro to thinking about controlling the rate of each stage.