Sending a Message Near and Far

Cell communication in multicellular organisms involves autocrine, paracrine, and endocrine signaling. Autocrine signaling enables a cell to regulate its own activity by releasing signaling molecules. Paracrine signaling affects nearby cells, while endocrine signaling releases molecules into the bloodstream, affecting distant target cells in tissues or organs.

Oh, Look…More Lymphocytes

The immune system involves more than just T cells, B cells, and ILCs. Other important lymphocyte populations include NK cells, γδ T cells, MAIT cells, DN T cells, LTi cells, IELs, and Tregs. These cells have diverse functions, such as detecting and eliminating infected or tumor cells, recognizing non-peptide antigens, contributing to tissue development, and regulating immune responses.