Previously, we have used a laborious method to identify splice variants of the various TRIM proteins. Moreover, we have not had a good method to quickly figure out what protein isoforms are possible from the splice variants.
Our lives just got easier with the discovery of SpliceMiner. Just go to this website and type in the name of the TRIM you’re working with. To try it out, I tried “TRIM6”. Immediately I was given the information to 10 splice variants and 4 protein isoforms.