Immune Cells Derived from the Various Progenitor Types

The differentiation of hematopoietic stem and progenitor cells leads to the generation of various fully differentiated blood cell types. Here are the main cell types derived from the following progenitor cell populations:

1. Common Myeloid Progenitor (CMP):
   • Fully-Differentiated Cells:
     • Erythrocytes (Red Blood Cells)
     • Megakaryocytes (Platelet-producing cells)
     • Granulocytes (Neutrophils, Basophils, Eosinophils)
     • Monocytes (Precursors to Macrophages and Dendritic Cells)
2. Megakaryocyte-Erythroid Progenitor (MEP):
   • Fully-Differentiated Cells:
     • Erythrocytes (Red Blood Cells)
     • Megakaryocytes (Platelet-producing cells)
3. Granulocyte-Macrophage Progenitor (GMP):
   • Fully-Differentiated Cells:
     • Neutrophils
     • Basophils
     • Eosinophils
     • Monocytes (Precursors to Macrophages and Dendritic Cells)
4. Common Lymphoid Progenitor (CLP):
   • Fully-Differentiated Cells:
     • T Lymphocytes (T Cells)
     • B Lymphocytes (B Cells)
     • Natural Killer (NK) Cells

More information about all of the differentiated cells listed above will be provided in future sections as this amazing story of how the immune system works unfolds.

Next Topic: Key Players in Regulating the Process of Hematopoiesis

Source: ChatGPT response prompted and edited by Joel Graff.

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