For Immunology Chapter 12 Day 3 The book made an analogy between B-1 B cells and γδ T cells. In what ways are these cell types similar? To what extent do B-1 B cells and MZ B cells rely on help from T cells? What other cells do these B cell subpopulations appear to interact … Continue reading B Cell Subsets (Some Similarities with T Cell Subsets)

For Immunology Chapter 12 Day 2 Activated B cells depart from their interaction with T cells at the T cell/B cell boundary and head either to the extrafollicular area to immediately begin developing into plasma cells or to the germinal centers (GC) where they go on to interact with FDC and TFH. Explain which activated … Continue reading B Cell Life after Split with T Cell

For Immunology Chapter 12 Day 1 What were some of the important ideas MacFarlane Burnett put forth in this “Clonal Selection Theory” publication? When B cells interact with CD4+ T cells that recognize the same antigen, there are three signals. Describe signals 1, 2, and 3 as well as the purpose of each of these … Continue reading B Cells Meet T Cells in the Middle