Antibody Somatic Recombination (Part 2): Armando Hasundungan

Topic: Antibody somatic (VDJ) recombination, a process that produces a unique antibody for immature B cells.

Two types of protein chains in antibodies: This process involves two types of light chains and one type of heavy chain.

Generation of Diversity (GOD): The mixing of variable regions, diverse regions, and joining segments creates a diverse range of antibodies. The video explains the process of heavy and light chain gene recombination, including DJ recombination and VDJ recombination, where new nucleotides can be added to increase diversity.

Enzymes involved: The video also discusses the proteins involved in the recombinational process and how recombination signal sequences can vary.

Leave a Reply

Fill in your details below or click an icon to log in:

WordPress.com Logo

You are commenting using your WordPress.com account. Log Out /  Change )

Twitter picture

You are commenting using your Twitter account. Log Out /  Change )

Facebook photo

You are commenting using your Facebook account. Log Out /  Change )

Connecting to %s