Antibody Somatic Recombination (Part 2): Armando Hasundungan

https://youtu.be/_D2x-dhh6Pg Topic: Antibody somatic (VDJ) recombination, a process that produces a unique antibody for immature B cells. Two types of protein chains in antibodies: This process involves two types of light chains and one type of heavy chain. Generation of Diversity (GOD): The mixing of variable regions, diverse regions, and joining segments creates a diverse … Continue reading Antibody Somatic Recombination (Part 2): Armando Hasundungan

Antibody Somatic Recombination (Part 1): Armando Hasundungan

https://youtu.be/h9mqsllg1Cs Topic: Antibody somatic recombination, also known as VDJ recombination, which occurs in B-cells. Two recombination events: The process involves two somatic recombinations: one in the heavy chain and another in the light chain. Heavy chain VDJ recombination: The heavy chain gene consists of a leader segment, a variable region, a diversity segment, a joining … Continue reading Antibody Somatic Recombination (Part 1): Armando Hasundungan