For Immunology Chapter 7 Day 3 Discuss the purpose of the VpreB, 5λ, and pre-Tα proteins. There are two points in the flow chart of figure 7-11 where a B cell may choose to die. What has to happen to get these two points?  Why does the B cell get more “chances to live” when … Continue reading Putting Lymphoid Cell Receptors Together

For Immunology Chapter 7 Day 2 Draw figure 7-5 and then explain why the V and J segments are capable of being recombined in light chains, but not heavy chains, of BCRs. When two V region segments are joined together, the sequence between the V and J, V and D (as well as D and J … Continue reading Mechanism of V(D)J Recombination