B Cells and Antibodies

Biotechnology Chapter 6 Day 1 Questions

1. Compare and contrast antigens and immunogens.
2. Draw an antibody and label important parts. Describe the function of each part.
3. Draw an antibody that has been digested with papain. How do the heavy and light chain fragments hold together following this cleavage event?
4. When are DNA recombination and mRNA splicing relevant to antibody (B cell receptor) expression?
5. What are the characteristics of the two cells that are fused together to form a hybridoma?
6. What is opsonization and what does it mean?
7. How is humanizing an antibody similar to developing CAR-T cells?
8. Contrast the mechanism of action for Herceptin and Remicade.